Abstract

The contact map of a protein fold is a graph that represents the patterns of contacts in the fold. It is known that the contact map can be decomposed into stacks and queues. RNA secondary structures are special stacks in which the degree of each vertex is at most one and each arc has length at least two. Waterman and Smith derived a formula for the number of RNA secondary structures of length nn with exactly kk arcs. Höner zu Siederdissen et al. developed a folding algorithm for extended RNA secondary structures in which each vertex has maximum degree two. An equation for the generating function of extended RNA secondary structures was obtained by Müller and Nebel by using a context-free grammar approach, which leads to an asymptotic formula. In this paper, we consider mm-regular linear stacks, where each arc has length at least mm and the degree of each vertex is bounded by two. Extended RNA secondary structures are exactly 22-regular linear stacks. For any m≥2m\geq 2, we obtain an equation for the generating function of the mm-regular linear stacks. For given mm, we can deduce a recurrence relation and an asymptotic formula for the number of mm-regular linear stacks on nn vertices. To establish the equation, we use the reduction operation of Chen, Deng and Du to transform an mm-regular linear stack to an mm-reduced zigzag (or alternating) stack. Then we find an equation for mm-reduced zigzag stacks leading to an equation for mm-regular linear stacks.

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