Paper detail

Translation by adaptor-helicase cycle in oligomer world

A mechanism of the translation in oligomer world is proposed. The translation is carried out by a minimum cycle, which is sustained by adaptors and helicases, and the first information processing in oligomer world. We expect that such a cycle actually worked in a primitive cell and can be constructed in vitro. By computer simulation we have shown that a proofreading is achieved by the fluctuation in the cell. It is rather paradoxical that the proofreading is effective for the system consisting of molecular machines with low efficiency.