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The number of rational numbers determined by large sets of integers

When $A$ and $B$ are subsets of the integers in $[1,X]$ and $[1,Y]$ respectively, with $|A| \geq αX$ and $|B| \geq βX$, we show that the number of rational numbers expressible as $a/b$ with $(a,b)$ in $A \times B$ is $\gg (αβ)^{1+ε}XY$ for any $ε> 0$, where the implied constant depends on $ε$ alone. We then construct examples that show that this bound cannot in general be improved to $\gg αβXY$. We also resolve the natural generalisation of our problem to arbitrary subsets $C$ of the integer points in $[1,X] \times [1,Y]$. Finally, we apply our results to answer a question of Sárközy concerning the differences of consecutive terms of the product sequence of a given integer sequence.