Abstract

Given a string ww over a finite alphabet ΣΣ and an integer KK, can ww be partitioned into strings of length at most KK, such that there are no \emph{collisions}? We refer to this question as the \emph{string partition} problem and show it is \NP-complete for various definitions of collision and for a number of interesting restrictions including ∣Σ∣=2|Σ|=2. This establishes the hardness of an important problem in contemporary synthetic biology, namely, oligo design for gene synthesis.

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