Rigorous results for a population model with selection I: evolution of the fitness distribution

preprint2015arXivOpen access

Abstract

We consider a model of a population of fixed size NN undergoing selection. Each individual acquires beneficial mutations at rate μNμ_N, and each beneficial mutation increases the individual's fitness by sNs_N. Each individual dies at rate one, and when a death occurs, an individual is chosen with probability proportional to the individual's fitness to give birth. Under certain conditions on the parameters μNμ_N and sNs_N, we obtain rigorous results for the rate at which mutations accumulate in the population and the distribution of the fitnesses of individuals in the population at a given time. Our results confirm predictions of Desai and Fisher (2007).

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