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Radiation stability of biocompatibile magnetic fluid

The radiation stability of biocompatibile magnetic fluid used in nanomedicine after electron irradiation was studied. Two types of the water-based magnetic fluids were prepared. The first one was based on the magnetite nanoparticles stabilized by one surfactant natrium oleate. The second one was biocompatibile magnetic fluid stabilized with two surfactants, natrium oleate as a first surfactant and Poly(ethylene glycol) (PEG) as a second surfactant. The magnetization measurements showed that electron irradiation up to 1000Gy caused 50% reduction of saturation magnetization in the case of the first sample with only one surfactant while in the case of the second biocompatibile magnetic fluid, only 25% reduction of saturation magnetization was observed. In the first magnetic fluid the radiation caused the higher sedimentation of the magnetic particles than in the second case, when magnetic particles are covered also with PEG. The obtained results show that PEG behave as a protective element.