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Optimal personalized therapies in colon-cancer induced immune response using a Fokker-Planck framework

In this paper, a new stochastic framework to determine optimal combination therapies in colon cancer-induced immune response is presented. The dynamics of colon cancer is described through an Itö stochastic process, whose probability density function evolution is governed by the Fokker-Planck equation. An open-loop control optimization problem is proposed to determine the optimal combination therapies. Numerical results with combination therapies comprising of the chemotherapy drug \ind{Doxorubicin} and immunotherapy drug IL-2 validate the proposed framework.

preprint2022arXivOpen access
Souvik RoySuvra Pal
math.OC
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Open access2 authors1 topic
Imported metadata coverageMissing code, dataset, citation and institution fields are tracked without dominating the paper.Details
Citations: 0Reviews: 0Saves: 0Code: not linkedDataset: not linkedInstitutions: 0

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Souvik RoySuvra Pal

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