Multiscale Analysis for a Vector-Borne Epidemic Model

Traditional studies about disease dynamics have focused on global stability issues, due to their epidemiological importance. We study a classical SIR-SI model for arboviruses in two different directions: we begin by describing an alternative proof of previously known global stability results by using only a Lyapunov approach. In the sequel, we take a different view and we argue that vectors and hosts can have very distinctive intrinsic time-scales, and that such distinctiveness extends to the disease dynamics. Under these hypothesis, we show that two asymptotic regimes naturally appear: the fast host dynamics and the fast vector dynamics. The former regime yields, at leading order, a SIR model for the hosts, but with a rational incidence rate. In this case, the vector disappears from the model, and the dynamics is similar to a directly contagious disease. The latter yields a SI model for the vectors, with the hosts disappearing from the model. Numerical results show the performance of the approximation, and a rigorous proof validates the reduced models.

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