Improved Constructions for Non-adaptive Threshold Group Testing

preprint2013arXivOpen access

Abstract

The basic goal in combinatorial group testing is to identify a set of up to dd defective items within a large population of size n≫dn \gg d using a pooling strategy. Namely, the items can be grouped together in pools, and a single measurement would reveal whether there are one or more defectives in the pool. The threshold model is a generalization of this idea where a measurement returns positive if the number of defectives in the pool reaches a fixed threshold u>0u > 0, negative if this number is no more than a fixed lower threshold ℓ<u\ell < u, and may behave arbitrarily otherwise. We study non-adaptive threshold group testing (in a possibly noisy setting) and show that, for this problem, O(dg+2(log⁡d)log⁡(n/d))O(d^{g+2} (\log d) \log(n/d)) measurements (where g:=u−ℓ−1g := u-\ell-1 and uu is any fixed constant) suffice to identify the defectives, and also present almost matching lower bounds. This significantly improves the previously known (non-constructive) upper bound O(du+1log⁡(n/d))O(d^{u+1} \log(n/d)). Moreover, we obtain a framework for explicit construction of measurement schemes using lossless condensers. The number of measurements resulting from this scheme is ideally bounded by O(dg+3(log⁡d)log⁡n)O(d^{g+3} (\log d) \log n). Using state-of-the-art constructions of lossless condensers, however, we obtain explicit testing schemes with O(dg+3(log⁡d)qpoly(log⁡n))O(d^{g+3} (\log d) qpoly(\log n)) and O(dg+3+βpoly(log⁡n))O(d^{g+3+β} poly(\log n)) measurements, for arbitrary constant β>0β> 0.

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