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Flavor hierarchies and B-anomalies from 5D

$B$-anomalies may suggest New Physics at the TeV scale breaking flavor universality. In particular, 4321 gauge models can successfully explain them in a consistent way. In this talk we explore how to UV complete the 4321 model in a 5D warped background to solve simultaneously the Higgs hierarchy problem too, finding interesting connections with the flavor puzzle. We present a model that addresses the $B$-anomalies, flavor hierarchies, and the Higgs hierarchy problem, where quarks and leptons are unified à la Pati-Salam in a non-universal way, and the Higgs appears as a pseudo-Nambu-Goldstone boson. These proceedings are based on arXiv:2203.01952.