Abstract
We study the conformational properties of heteropolymers containing two types of monomers A and B, modeled as self-avoiding random walks on a regular lattice. Such a model can describe in particular the sequences of hydrophobic and hydrophilic residues in proteins (K.F. Lau and K.A. Dill, Macromolecules {\bf 22}, 3986 (1989)) and polyampholytes with oppositely charged groups (Y. Kantor and M. Kardar, Europhys. Lett.{\bf 28}, 169 (1994)). Treating the sequences of the two types of monomers as quenched random variables, we provide a systematic analysis of possible generalizations of this model. To this end we apply the pruned-enriched Rosenbluth chain-growth algorithm (PERM), which allows us to obtain the phase diagrams of extended and compact states coexistence as function of both the temperature and fraction of A and B monomers along the heteropolymer chain.
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