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Analysis of the spatial and dynamical properties of a multiscale model of intestinal crypts

The preliminary analyses on a multiscale model of intestinal crypt dynamics are here presented. The model combines a morphological model, based on the Cellular Potts Model (CPM), and a gene regulatory network model, based on Noisy Random Boolean Networks (NRBNs). Simulations suggest that the stochastic differentiation process is itself sufficient to ensure the general homeostasis in the asymptotic states, as proven by several measures.

preprint2013arXivOpen access
Giulio CaravagnaAlex GraudenziMarco AntoniottiGiovanni de Matteis
Cell BehaviorComputational Engineering, Finance, and ScienceDiscrete MathematicsComputational Geometry
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Open access4 authors4 topics
Imported metadata coverageMissing code, dataset, citation and institution fields are tracked without dominating the paper.Details
Citations: 0Reviews: 0Saves: 0Code: not linkedDataset: not linkedInstitutions: 0

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Giulio CaravagnaAlex GraudenziMarco AntoniottiGiovanni de Matteis

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