An exact algorithm for the weighed mutually exclusive maximum set cover problem

preprint2014arXivOpen access

Abstract

In this paper, we introduce an exact algorithm with a time complexity of O∗(1.325m)O^*(1.325^m) for the {\sc weighted mutually exclusive maximum set cover} problem, where mm is the number of subsets in the problem. This is an NP-hard motivated and abstracted from a bioinformatics problem of identifying signaling pathways based gene mutations. Currently, this problem is addressed using heuristic algorithms, which cannot guarantee the performance of the solution. By providing a relatively efficient exact algorithm, our approach will like increase the capability of finding better solutions in the application of cancer research.

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