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PCA Rerandomization

Mahalanobis distance between treatment group and control group covariate means is often adopted as a balance criterion when implementing a rerandomization strategy. However, this criterion may not work well for high-dimensional cases because it balances all orthogonalized covariates equally. Here, we propose leveraging principal component analysis (PCA) to identify proper subspaces in which Mahalanobis distance should be calculated. Not only can PCA effectively reduce the dimensionality for high-dimensional cases while capturing most of the information in the covariates, but it also provides computational simplicity by focusing on the top orthogonal components. We show that our PCA rerandomization scheme has desirable theoretical properties on balancing covariates and thereby on improving the estimation of average treatment effects. We also show that this conclusion is supported by numerical studies using both simulated and real examples.