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Zhenlin Xu

Zhenlin Xu contributes to research discovery and scholarly infrastructure.

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Published work

5 published item(s)

preprint2026arXiv

PPU-Bench:Real World Benchmark for Personalized Partial Unlearning in Vision Language Models

Multimodal Large Language Models (MLLMs) may memorize sensitive cross-modal information during pretraining. However, existing MLLM unlearning benchmarks rely on synthetic knowledge injection or complete subject-level deletion, which fail to capture realistic, personalized deletion requests that require fine-grained factual control. In this paper, we introduce PPU-Bench, a real-world and fine-tuning-free benchmark for personalized partial unlearning in MLLMs. PPU-Bench contains 24K multimodal and unimodal samples derived from pre-existing knowledge of 500 public figures under three progressively challenging settings: Complete, Selective, and Personalized unlearning. The benchmark evaluates whether methods can remove target knowledge while preserving non-target facts, model utility, and cross-modal consistency. Extensive experiments show that Complete Unlearning often suppresses visual identity rather than factual knowledge, while Selective and Personalized Unlearning expose significant forget--retain trade-offs and challenges in intra-subject factual boundaries. Robustness analysis under cross-image and prompt-based attacks reveals distinct vulnerabilities across different unlearning settings. Motivated by these findings, we propose Boundary-Aware Optimization (BAO), which explicitly models intra-subject forget-retain boundaries. Experimental results on two representative methods demonstrate that BAO can effectively enforce intra-subject factual boundaries.

preprint2023arXiv

Improving Dense Contrastive Learning with Dense Negative Pairs

Many contrastive representation learning methods learn a single global representation of an entire image. However, dense contrastive representation learning methods such as DenseCL (Wang et al., 2021) can learn better representations for tasks requiring stronger spatial localization of features, such as multi-label classification, detection, and segmentation. In this work, we study how to improve the quality of the representations learned by DenseCL by modifying the training scheme and objective function, and propose DenseCL++. We also conduct several ablation studies to better understand the effects of: (i) various techniques to form dense negative pairs among augmentations of different images, (ii) cross-view dense negative and positive pairs, and (iii) an auxiliary reconstruction task. Our results show 3.5% and 4% mAP improvement over SimCLR (Chen et al., 2020a) andDenseCL in COCO multi-label classification. In COCO and VOC segmentation tasks, we achieve 1.8% and 0.7% mIoU improvements over SimCLR, respectively.

preprint2022arXiv

iSegFormer: Interactive Segmentation via Transformers with Application to 3D Knee MR Images

We propose iSegFormer, a memory-efficient transformer that combines a Swin transformer with a lightweight multilayer perceptron (MLP) decoder. With the efficient Swin transformer blocks for hierarchical self-attention and the simple MLP decoder for aggregating both local and global attention, iSegFormer learns powerful representations while achieving high computational efficiencies. Specifically, we apply iSegFormer to interactive 3D medical image segmentation.

preprint2020arXiv

A Deep Network for Joint Registration and Reconstruction of Images with Pathologies

Registration of images with pathologies is challenging due to tissue appearance changes and missing correspondences caused by the pathologies. Moreover, mass effects as observed for brain tumors may displace tissue, creating larger deformations over time than what is observed in a healthy brain. Deep learning models have successfully been applied to image registration to offer dramatic speed up and to use surrogate information (e.g., segmentations) during training. However, existing approaches focus on learning registration models using images from healthy patients. They are therefore not designed for the registration of images with strong pathologies for example in the context of brain tumors, and traumatic brain injuries. In this work, we explore a deep learning approach to register images with brain tumors to an atlas. Our model learns an appearance mapping from images with tumors to the atlas, while simultaneously predicting the transformation to atlas space. Using separate decoders, the network disentangles the tumor mass effect from the reconstruction of quasi-normal images. Results on both synthetic and real brain tumor scans show that our approach outperforms cost function masking for registration to the atlas and that reconstructed quasi-normal images can be used for better longitudinal registrations.

preprint2020arXiv

Anatomical Data Augmentation via Fluid-based Image Registration

We introduce a fluid-based image augmentation method for medical image analysis. In contrast to existing methods, our framework generates anatomically meaningful images via interpolation from the geodesic subspace underlying given samples. Our approach consists of three steps: 1) given a source image and a set of target images, we construct a geodesic subspace using the Large Deformation Diffeomorphic Metric Mapping (LDDMM) model; 2) we sample transformations from the resulting geodesic subspace; 3) we obtain deformed images and segmentations via interpolation. Experiments on brain (LPBA) and knee (OAI) data illustrate the performance of our approach on two tasks: 1) data augmentation during training and testing for image segmentation; 2) one-shot learning for single atlas image segmentation. We demonstrate that our approach generates anatomically meaningful data and improves performance on these tasks over competing approaches. Code is available at https://github.com/uncbiag/easyreg.