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Researcher profile

Zaiqing Nie

Zaiqing Nie contributes to research discovery and scholarly infrastructure.

ResearcherAffiliation not importedOpen to collaborate
Artificial IntelligenceComputation and LanguageComputer VisionInformation RetrievalQuantitative Methods

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Published work

4 published item(s)

preprint2026arXiv

Co-Generative De Novo Functional Protein Design

De novo functional protein design aims to generate protein sequences that realize specified biochemical functions without relying on evolutionary templates, enabling broad applications in biotechnology and medicine. Existing approaches adopt either direct function-to-sequence mapping or decoupled structure-sequence generation strategies but often fail to achieve functionality and foldability simultaneously. To address this, we propose CodeFP, a Co-generative protein language model for de novo Functional Protein design that simultaneously decodes sequence and structure tokens, thereby enabling superior simultaneous realization of functionality and foldability. CodeFP utilizes functional local structures to enrich functional semantic encodings, overcoming the suboptimal translation of flat encodings into structure tokens, while introducing auxiliary functional supervision to alleviate training ambiguity stemming from the one-to-many structure-to-token mapping. Extensive experiments show that CodeFP consistently achieves average improvements of 6.1% in functional consistency and 3.2% in foldability over the strongest baseline.

0 citations0 reviewsNo code linkedOpen access
preprint2022arXiv

DAIR-V2X: A Large-Scale Dataset for Vehicle-Infrastructure Cooperative 3D Object Detection

Autonomous driving faces great safety challenges for a lack of global perspective and the limitation of long-range perception capabilities. It has been widely agreed that vehicle-infrastructure cooperation is required to achieve Level 5 autonomy. However, there is still NO dataset from real scenarios available for computer vision researchers to work on vehicle-infrastructure cooperation-related problems. To accelerate computer vision research and innovation for Vehicle-Infrastructure Cooperative Autonomous Driving (VICAD), we release DAIR-V2X Dataset, which is the first large-scale, multi-modality, multi-view dataset from real scenarios for VICAD. DAIR-V2X comprises 71254 LiDAR frames and 71254 Camera frames, and all frames are captured from real scenes with 3D annotations. The Vehicle-Infrastructure Cooperative 3D Object Detection problem (VIC3D) is introduced, formulating the problem of collaboratively locating and identifying 3D objects using sensory inputs from both vehicle and infrastructure. In addition to solving traditional 3D object detection problems, the solution of VIC3D needs to consider the temporal asynchrony problem between vehicle and infrastructure sensors and the data transmission cost between them. Furthermore, we propose Time Compensation Late Fusion (TCLF), a late fusion framework for the VIC3D task as a benchmark based on DAIR-V2X. Find data, code, and more up-to-date information at https://thudair.baai.ac.cn/index and https://github.com/AIR-THU/DAIR-V2X.

0 citations0 reviewsNo code linkedOpen access
preprint2022arXiv

Federated Learning for Personalized Humor Recognition

Computational understanding of humor is an important topic under creative language understanding and modeling. It can play a key role in complex human-AI interactions. The challenge here is that human perception of humorous content is highly subjective. The same joke may receive different funniness ratings from different readers. This makes it highly challenging for humor recognition models to achieve personalization in practical scenarios. Existing approaches are generally designed based on the assumption that users have a consensus on whether a given text is humorous or not. Thus, they cannot handle diverse humor preferences well. In this paper, we propose the FedHumor approach for the recognition of humorous content in a personalized manner through Federated Learning (FL). Extending a pre-trained language model, FedHumor guides the fine-tuning process by considering diverse distributions of humor preferences from individuals. It incorporates a diversity adaptation strategy into the FL paradigm to train a personalized humor recognition model. To the best of our knowledge, FedHumor is the first text-based personalized humor recognition model through federated learning. Extensive experiments demonstrate the advantage of FedHumor in recognizing humorous texts compared to nine state-of-the-art humor recognition approaches with superior capability for handling the diversity in humor labels produced by users with diverse preferences.

0 citations0 reviewsNo code linkedOpen access
preprint2021arXiv

Learning Hierarchical Review Graph Representations for Recommendation

The user review data have been demonstrated to be effective in solving different recommendation problems. Previous review-based recommendation methods usually employ sophisticated compositional models, such as Recurrent Neural Networks (RNN) and Convolutional Neural Networks (CNN), to learn semantic representations from the review data for recommendation. However, these methods mainly capture the local dependency between neighbouring words in a word window, and they treat each review equally. Therefore, they may not be effective in capturing the global dependency between words, and tend to be easily biased by noise review information. In this paper, we propose a novel review-based recommendation model, named Review Graph Neural Network (RGNN). Specifically, RGNN builds a specific review graph for each individual user/item, which provides a global view about the user/item properties to help weaken the biases caused by noise review information. A type-aware graph attention mechanism is developed to learn semantic embeddings of words. Moreover, a personalized graph pooling operator is proposed to learn hierarchical representations of the review graph to form the semantic representation for each user/item. We compared RGNN with state-of-the-art review-based recommendation approaches on two real-world datasets. The experimental results indicate that RGNN consistently outperforms baseline methods, in terms of Mean Square Error (MSE).

0 citations0 reviewsNo code linkedOpen access