Researcher profile

Xinhao Hu

Xinhao Hu contributes to research discovery and scholarly infrastructure.

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Published work

2 published item(s)

preprint2026arXiv

Enhancing Domain Generalization in 3D Human Pose Estimation through Controllable Generative Augmentation

Pedestrian motion, due to its causal nature, is strongly influenced by domain gaps arising from discrepancies between training and testing data distributions. Focusing on 3D human pose estimation, this work presents a controllable human pose generation framework that synthesizes diverse video data by systematically varying poses, backgrounds, and camera viewpoints. This generative augmentation enriches training datasets, enhances model generalization, and alleviates the limitations of existing methods in handling domain discrepancies. By leveraging both indoor/real-world and outdoor/virtual datasets, we perform cross-domain data fusion and controllable video generation to construct enriched training data, tailored to realistic deployment settings. Extensive experiments show that the augmented datasets significantly improve model performance on unseen scenarios and datasets, validating the effectiveness of the proposed approach.

preprint2026arXiv

Nanodiamond-Enabled Torsion Microscopy Uncovers Multidimensional Cell-Matrix Mechanical Interactions

Traditional cellular force-sensing techniques, such as traction force microscopy (TFM), are predominantly limited to measuring linear tractions, overlooking and technically unable to capture the nanoscale torsional forces that are critical in cell-matrix interactions. Here, we introduce a nanodiamond-enabled torsion microscopy (DTM) that integrates nitrogen-vacancy (NV) centers as orientation markers with micropillar arrays to decouple and quantify nanoscale rotational and translational motions induced by cells. This approach achieves high precision (~1.47 degree rotational accuracy and ~3.13*10-15 Nm torque sensitivity), enabling reconstruction of cellular torsional force fields and twisting energy distributions previously underestimated. Our findings reveal the widespread presence of torsional forces in cell-matrix interactions, introducing "cellular mechanical modes" where different adhesion patterns dictate the balance between traction- and torque- mediated mechanical energy transferred to the substrate. Notably, in immune cells like macrophages that generally exert low linear tractions, torque overwhelmingly dominates traction, highlighting a unique mechanical output for specific cellular functions. By uncovering these differential modes, DTM provides a versatile tool to advance biomechanical investigations, with potential applications in disease diagnostics and therapeutics.