Researcher profile

Se Young Chun

Se Young Chun contributes to research discovery and scholarly infrastructure.

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Published work

4 published item(s)

preprint2026arXiv

A Target-Free Harmonization Method for MRI

In MRI, variations in scan parameters, sequence, or hardware can lead to discrepancies in image appearance, even for the same subject. These inconsistencies, known as domain shifts, can hinder image analysis and degrade the performance of deep learning models trained on data from specific target domains. MRI image harmonization aims to address these issues by aligning source domain images to the target domain images while preserving biological information such as anatomical structures. However, most existing harmonization approaches require access to both source and target domain data in training or test time. This dependence induces data sharing between institutions, raising concerns about patient privacy and substantially limiting the harmonization approaches that can be practically deployed in clinical settings. To overcome these limitations, we introduce TgtFreeHarmony, the harmonization framework tailored for target-free scenarios, eliminating the need for target domain data and any data sharing, enabling privacy-preserving harmonization directly within the source institution. Our approach estimates the target domain style by searching the manifold of MRI domain style constructed via a disentanglement-based generator using Bayesian optimization guided by the performance of a downstream task model, which is trained on target domain data. We evaluated our method on the brain tissue segmentation task across multiple institutes and demonstrated that it effectively harmonizes source images into target images, leading to improved downstream task performance. By enabling harmonization without any access to target-domain data, TgtFreeHarmony establishes a new direction of harmonization preserving data privacy that can be realistically deployed within clinical environments.

preprint2022arXiv

Adaptive GLCM sampling for transformer-based COVID-19 detection on CT

The world has suffered from COVID-19 (SARS-CoV-2) for the last two years, causing much damage and change in people's daily lives. Thus, automated detection of COVID-19 utilizing deep learning on chest computed tomography (CT) scans became promising, which helps correct diagnosis efficiently. Recently, transformer-based COVID-19 detection method on CT is proposed to utilize 3D information in CT volume. However, its sampling method for selecting slices is not optimal. To leverage rich 3D information in CT volume, we propose a transformer-based COVID-19 detection using a novel data curation and adaptive sampling method using gray level co-occurrence matrices (GLCM). To train the model which consists of CNN layer, followed by transformer architecture, we first executed data curation based on lung segmentation and utilized the entropy of GLCM value of every slice in CT volumes to select important slices for the prediction. The experimental results show that the proposed method improve the detection performance with large margin without much difficult modification to the model.

preprint2022arXiv

Self-supervised regression learning using domain knowledge: Applications to improving self-supervised denoising in imaging

Regression that predicts continuous quantity is a central part of applications using computational imaging and computer vision technologies. Yet, studying and understanding self-supervised learning for regression tasks - except for a particular regression task, image denoising - have lagged behind. This paper proposes a general self-supervised regression learning (SSRL) framework that enables learning regression neural networks with only input data (but without ground-truth target data), by using a designable pseudo-predictor that encapsulates domain knowledge of a specific application. The paper underlines the importance of using domain knowledge by showing that under different settings, the better pseudo-predictor can lead properties of SSRL closer to those of ordinary supervised learning. Numerical experiments for low-dose computational tomography denoising and camera image denoising demonstrate that proposed SSRL significantly improves the denoising quality over several existing self-supervised denoising methods.

preprint2021arXiv

Image Restoration by Deep Projected GSURE

Ill-posed inverse problems appear in many image processing applications, such as deblurring and super-resolution. In recent years, solutions that are based on deep Convolutional Neural Networks (CNNs) have shown great promise. Yet, most of these techniques, which train CNNs using external data, are restricted to the observation models that have been used in the training phase. A recent alternative that does not have this drawback relies on learning the target image using internal learning. One such prominent example is the Deep Image Prior (DIP) technique that trains a network directly on the input image with a least-squares loss. In this paper, we propose a new image restoration framework that is based on minimizing a loss function that includes a "projected-version" of the Generalized SteinUnbiased Risk Estimator (GSURE) and parameterization of the latent image by a CNN. We demonstrate two ways to use our framework. In the first one, where no explicit prior is used, we show that the proposed approach outperforms other internal learning methods, such as DIP. In the second one, we show that our GSURE-based loss leads to improved performance when used within a plug-and-play priors scheme.