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Ming Liu

Ming Liu contributes to research discovery and scholarly infrastructure.

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Trust 21 - EmergingVerification L1Unclaimed author
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Published work

9 published item(s)

preprint2026arXiv

A volume penalization method for solving conjugate scalar transport with interfacial jump conditions

Conjugate scalar transport with interfacial jump conditions on complex interfacial geometries is common in thermal and chemical processes, while its accurate and efficient simulations are still quite challenging. In the present study, a novel treatment of a two-phase interface in the volume penalization method, a kind of immersed boundary method, for solving conjugate scalar transport with general interfacial boundary conditions is developed. We first propose an interfacial treatment for solving an advection-diffusion equation with a Neumann boundary condition, and then extend it to general conjugate scalar transport with both interfacial flux and scalar jumps. A one-dimensional diffusion problem is solved to verify the present scheme and demonstrate the advantage of the present scheme in improving accuracy and unifying the governing equations in the two phases with an additional source term representing the local jump condition of the interfacial scalar flux. Then, the present scheme is further applied to fluid-solid coupled scalar diffusion and advection-diffusion problems with the scalar and its flux jumps across the interface. The simulation results of the present scheme generally show good agreement with reference results obtained by body-fitted mesh simulations with average relative deviations less than 3.0%.

preprint2026arXiv

Analyzing Reasoning Consistency in Large Multimodal Models under Cross-Modal Conflicts

Large Multimodal Models (LMMs) have demonstrated impressive capabilities in video reasoning via Chain-of-Thought (CoT). However, the robustness of their reasoning chains remains questionable. In this paper, we identify a critical failure mode termed textual inertia, where once a textual hallucination occurs in the thinking process, models tend to blindly adhere to the erroneous text while neglecting conflicting visual evidence. To systematically investigate this, we propose the LogicGraph Perturbation Protocol that structurally injects perturbations into the reasoning chains of diverse LMMs spanning both native reasoning architectures and prompt-driven paradigms to evaluate their self-reflection capabilities. The results reveal that models successfully self-correct in less than 10% of cases and predominantly succumb to blind textual error propagation. To mitigate this, we introduce Active Visual-Context Refinement, a training-free inference paradigm which orchestrates an active visual re-grounding mechanism to enforce fine-grained verification coupled with an adaptive context refinement strategy to summarize and denoise the reasoning history. Experiments demonstrate that our approach significantly stifles hallucination propagation and enhances reasoning robustness.

preprint2026arXiv

Central elements and evaluation map for the quantum queer superalgebras

We consider the $R$-matrix presentations of the quantum queer superalgebra $U_q(q_n)$ and its affine counterpart $U_q(\widehat q_n)$. We derive crossing symmetry relations for the $R$-matrices and use them to construct central elements in both superalgebras. We also produce an epimorphism $ev:U_q(\widehat q_n)\to U_q(q_n)$ identical on the subalgebra isomorphic to $U_q(q_n)$.

preprint2026arXiv

EGL-SCA: Structural Credit Assignment for Co-Evolving Instructions and Tools in Graph Reasoning Agents

Graph reasoning agents operating from natural-language inputs must solve a coupled problem: they must reconstruct a structured graph instance from text, decide whether existing computational assets are sufficient, interact with tools under a strict execution protocol, and satisfy an external verifier that checks structured correctness rather than textual plausibility. Existing approaches usually improve either the instruction side or the tool side in isolation, which leaves unclear what should be updated after failure. We propose EGL-SCA, a verifier-centric dual-space framework that models a graph reasoning agent using two collaborative components: an instruction-side policy space for reasoning strategies, and a tool-side program space for executable algorithmic tools. Our central mechanism is structural credit assignment, which maps trajectory evidence to conditional updates, precisely routing failures to either prompt optimization or tool synthesis and repair. To provide sufficient learning signals for dual-space adaptation, we introduce a training distribution stratified by task family, coupled with a Pareto-style retention strategy to balance success, generality, and parsimony. Experiments on four graph reasoning benchmarks show that EGL-SCA achieves a state-of-the-art 92.0\% average success rate. By effectively co-evolving instructions and tools, our framework significantly outperforms both pure-prompting and fixed-toolbox baselines.

preprint2026arXiv

Electric field switching of altermagnetic spin-splitting in multiferroic skyrmions

Magnetic skyrmions are localized magnetic structures that retain their shape and stability over time, thanks to their topological nature. Recent theoretical and experimental progress has laid the groundwork for understanding magnetic skyrmions characterized by negligible net magnetization and ultrafast dynamics. Notably, skyrmions emerging in materials with altermagnetism, a novel magnetic phase featuring lifted Kramers degeneracy-have remained unreported until now. In this study, we demonstrate that BiFeO3, a multiferroic renowned for its strong coupling between ferroelectricity and magnetism, can transit from a spin cycloid to a Neel-type skyrmion under antidamping spin-orbit torque at room temperature. Strikingly, the altermagnetic spin splitting within BiFeO3 skyrmion can be reversed through the application of an electric field, revealed via the Circular photogalvanic effect. This quasiparticle, which possesses a neutral topological charge, holds substantial promise for diverse applications-most notably, enabling the development of unconventional computing systems with low power consumption and magnetoelectric controllability.

preprint2026arXiv

From Bench to Bedside: A Review of Clinical Trials in Drug Discovery and Development

Clinical trials are an indispensable part of the drug development process, bridging the gap between basic research and clinical application. During the development of new drugs, clinical trials are used not only to evaluate the safety and efficacy of the drug but also to explore its dosage, treatment regimens, and potential side effects. This review discusses the various stages of clinical trials, including Phase I (safety assessment), Phase II (preliminary efficacy evaluation), Phase III (large-scale validation), and Phase IV (post-marketing surveillance), highlighting the characteristics of each phase and their interrelationships. Additionally, the paper addresses the major challenges encountered in clinical trials, such as ethical issues, subject recruitment difficulties, diversity and representativeness concerns, and proposes strategies for overcoming these challenges. With the advancement of technology, innovative technologies such as artificial intelligence, big data, and digitalization are gradually transforming clinical trial design and implementation, improving trial efficiency and data quality. The article also looks forward to the future of clinical trials, particularly the impact of emerging therapies such as gene therapy and immunotherapy on trial design, as well as the importance of regulatory reforms and global collaboration. In conclusion, the core role of clinical trials in drug development will continue to drive the progress of innovative drug development and clinical treatment.

preprint2026arXiv

From In Silico to In Vitro: A Comprehensive Guide to Validating Bioinformatics Findings

The integration of bioinformatics predictions and experimental validation plays a pivotal role in advancing biological research, from understanding molecular mechanisms to developing therapeutic strategies. Bioinformatics tools and methods offer powerful means for predicting gene functions, protein interactions, and regulatory networks, but these predictions must be validated through experimental approaches to ensure their biological relevance. This review explores the various methods and technologies used for experimental validation, including gene expression analysis, protein-protein interaction verification, and pathway validation. We also discuss the challenges involved in translating computational predictions to experimental settings and highlight the importance of collaboration between bioinformatics and experimental research. Finally, emerging technologies, such as CRISPR gene editing, next-generation sequencing, and artificial intelligence, are shaping the future of bioinformatics validation and driving more accurate and efficient biological discoveries.

preprint2026arXiv

Volume penalization method for simulating flows around a rotating solid with multiple reference frame and sliding mesh

Despite the significant role of turbomachinery in fluid-based energy transfer, precise simulation of rotating solid objects with complex geometry is a challenging task. In the present study, the volume penalization method (VPM) is combined with multiple reference frame (MRF) and sliding mesh (SLM), respectively, so as to develop immersed-boundary approaches for simulating flows around a rotating solid. The level-set function is adopted to represent arbitrary geometries embedded in Cartesian grids. The VPM body-forcing terms in the momentum equation are proposed for MRF and SLM, respectively, so as to build unified governing equations for both fluid and solid regions. The flows around a rotating cuboid under various rotating speeds are simulated by the present schemes, namely, VPM with MRF, and VPM with SLM, and compared to corresponding simulations by the body-fitted method (BFM). The results suggest the relative deviations of predicted pressure drop and torque between the present VPM and BFM are around 5%, demonstrating the validity of the present VPM.

preprint2025arXiv

Text Anomaly Detection with Simplified Isolation Kernel

Two-step approaches combining pre-trained large language model embeddings and anomaly detectors demonstrate strong performance in text anomaly detection by leveraging rich semantic representations. However, high-dimensional dense embeddings extracted by large language models pose challenges due to substantial memory requirements and high computation time. To address this challenge, we introduce the Simplified Isolation Kernel (SIK), which maps high-dimensional dense embeddings to lower-dimensional sparse representations while preserving crucial anomaly characteristics. SIK has linear time complexity and significantly reduces space complexity through its innovative boundary-focused feature mapping. Experiments across 7 datasets demonstrate that SIK achieves better detection performance than 11 state-of-the-art (SOTA) anomaly detection algorithms while maintaining computational efficiency and low memory cost. All code and demonstrations are available at https://github.com/charles-cao/SIK.